Kozani, administratively, functions as a municipality, from 1879. Up to then, it was recognized as community. The current Mayor is Lazaros Maloutas, since 2009.
Nikolaos Chalkias (twice), Emmanouil M. Manos, Kotias Dardoufas, Nik. Rompapas (twice), Ioannis K. Govedaros (twice), Georgios Tsiminakis, Ioannis G. Govedaros, Georgios Handgiandreou (twice), Konstantinos A. Gagalis (twice), Stefanos G. Gortsoulis, Georgios Em. Manos, Nikolaos G. Armenoulis.
| # | Name | Took Office | Left Office | Party |
|---|---|---|---|---|
| 1st | Nikolaos Armenoulis | 1912 | 1913 | |
| 2nd | Georgios Manos | 1913 | 1915 | |
| 3rd | Konstantinos Gagalis | 1915 | 1916 | |
| 4th | Georgios Manos | 1916 | 1916 | |
| 5th | Georgios Delivanis | 1917 | 1919 | |
| 6th | Ilias Vamvakas | 1919 | 1920 | |
| 7th | Georgios Delivanis | 1920 | 1920 | |
| 8th | Nikolaos Tsiminakis | 1920 | 1920, 12 November | |
| 9th | Asterios Terpou | 1920, 13 November | 1922, 30 November | |
| 10th | Nikolaos Tsiminakis | 1922, 1 December | 1925, 3 September | |
| 11th | Ioannis Govedaros | 1925, 4 September | 1925, 30 December | |
| 12th | Asterios Terpou | 1925, 1 December | 1928, 24 February | |
| 13th | Argyrios Tsoumis | 1928, 24 February | 1929, 30 August | |
| 14th | Asterios Karagounis | 1929, 1 September | 1934 | |
| 15th | Asterios Terpou | 1934 | 1939 | |
| 16th | Charisios Govedaros | 1940 | 1945 | |
| 17th | Ioannis Goras | 1945 | 1945 | |
| 18th | Christakis Konstantinou | 1945 | 1945 | |
| 19th | Dimitrios Terpou | 1946 | 1950 | |
| 20th | Argyrios Tsoumis | 1951 | 1955 | |
| 21st | Vasilios Matiakis | 1955 | 1964 | |
| 22nd | Merkouris Kyratsous | 1964 | 1967 | |
| 23rd | Nikolaos Chasapis | 1967, 29 May | 1967, 31 August | |
| 24th | Konstantinos Polyzoulis | 1967, 1 September | 1971, 7 November | |
| 25th | Nikolaos Athanasiadis | 1971, 8 November | 1972, 28 January | |
| 26th | Konstantinos Polyzoulis | 1972, 29 January | 1973, 25 May | |
| 27th | Dimitrios Delialis | 1973, 26 May | 1974, 24 September | |
| 28th | Georgios Foskolos | 1974, 25 September | 1975, 31 May | |
| 29th | Ioannis Papagiannis | 1975, 1 June | 1982, 31 December | |
| 30th | Ioannis Pagounis | 1983, 1 January | 1990, 31 December | |
| 31st | Paraskeuas (Paris) Koukoulopoulos | 1991, 1 January | 2009, 21 September | |
| 32nd | Lazaros Maloutas | 2009, 22 September |